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BioLabDonkey

價格:免費

更新日期:2020-07-16

檔案大小:25.3 MB

目前版本:2.2

版本需求:macOS 10.12 或以上版本,64 位元處理器

支援語言:英語

BioLabDonkey(圖1)-速報App

This program is aimed at researches in the molecular biology field for use in their everyday routine work. It is a suite of the bioinformatic tools for the analysis of DNA, RNA, and protein sequences, as well as images of gels, blots, cells and colonies. It also provides a set of useful calculators for molecular biology.

The user interface was developed around a minimalistic design and ease of use, such as: direct access to functions in less than three clicks, essential functionality with a minimum of settings, minimisation of windows (uncluttered screen).

The program includes custom algorithms for: the protein/DNA sequences alignment, protein secondary structures prediction, RNA-seq differential expression.

Features:

- Open files with the extensions: .txt, .rtf, .fasta, .fas, .fa, .fsa, .ffn, .fna, .seq, .ape, .gb, .gbk, .ab1, .bldna, .xdna, .dna, .faa, .seq, .gp, .blprotein, .fastq, .aln, .blalignment, .pdb, .jpg, .tiff, .png. 

BioLabDonkey(圖2)-速報App

The program reads files created by Serial Cloner(.xdna), DNA Strider(.xdna), SnapGene(.dna) and ApE (.ape) programs.

- Save files with the extensions: .txt, .rtf, .fasta, .fas, .fa, .fsa, .ffn, .fna, .seq, .gb, .gbk, .ab1, .bldna, .faa, .seq, .gp, .blprotein, .blalignment, .pdf, .eps, jpg, png;

- Transcribe, reverse complement and translate DNA sequence;

- Tm, %GC, Mw, length of selected DNA and Mw (average and monoisotopic), length of protein;

- Find open reading frames (ORFs);

BioLabDonkey(圖3)-速報App

- Find sequence motifs (repeats, palindromes, stem loops and arbitrary sequences) in DNA sequence;

- Generate primers;

- View ABI sequencing chromatogram, edit sequence;

- Generate ORF silent mutations;

- Optimize codons in ORF;

BioLabDonkey(圖4)-速報App

- View GC content, CpG islands and Stem Loops;

- Generate Plasmid, Linear and Text map using feature annotations from genbank file;

- Generate and edit DNA/protein features for genbank/genpept format files;

- Generate DNA features database and perform features annotation;

- Copy/paste the selected DNA sequence with features;

BioLabDonkey(圖5)-速報App

- Find/highlight DNA restriction sites and DNA fragments;

- Genome viewer;

- Virtual DNA gel viewer;

- Multiple alignment and realignment of DNA/protein sequences;

- Assembly of sequencing reads from .ab1 or txt files;

BioLabDonkey(圖6)-速報App

- Phylogenetic trees;

- Protein/DNA/RNA PDB viewer;

- Prediction of protein secondary structures;

- Protein Hydropathicity/pI plots;

- Protein limited proteolysis;

BioLabDonkey(圖7)-速報App

- Find/highlight protease sites and protein fragments;

- RNA-Seq DE: genes and miRNAs differential expression;

- Calculators for: Dilution, Molarity, Ligation, SDS PAG, Ammonium sulfate, Bacteria growth;

- Nucleic acid OD conversion;

- Units conversion for DNA and protein;

BioLabDonkey(圖8)-速報App

- Colonies/Cells/Spots counting;

- Analysis of Gel/Blot photo and calculation of relative fold-change in selected Gel/Blot bands/spots;

- Image adjustment and labels.

BioLabDonkey(圖9)-速報App